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pentobarbital will lessen the level or impact of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Solid or moderate CYP3A4 inducers could maximize price of diazepam elimination; thus, efficacy of diazepam could be diminished.pentobarbital decreases effects of hemin by pharmacodynamic antagonism. U